{"id":423,"date":"2026-05-08T14:33:57","date_gmt":"2026-05-08T12:33:57","guid":{"rendered":"https:\/\/doktorpeptid.sk\/?post_type=product&#038;p=423"},"modified":"2026-11-10T08:52:22","modified_gmt":"2026-11-10T07:52:22","slug":"retatrutide","status":"publish","type":"product","link":"https:\/\/doktorpeptid.sk\/en\/product\/retatrutide\/","title":{"rendered":"Retatrutide (Retatrutid) 5, 10, 20 a 30 mg"},"content":{"rendered":"<h2>Retatrutide (Retatrutid) 5, 10, 20 a 30 mg \u2013 v\u00fdskumn\u00fd peptid skladom na Slovensku<\/h2>\n<p><strong>Retatrutide<\/strong> (po slovensky <strong>retatrutid<\/strong>, v\u00fdvojov\u00e9 ozna\u010denie <strong>LY3437943<\/strong>) je syntetick\u00fd peptid, ktor\u00fd p\u00f4sob\u00ed ako <strong>triple agonista<\/strong> troch metabolick\u00fdch receptorov \u2013 GIP, GLP-1 a glukag\u00f3nov\u00e9ho receptora. V DoktorPeptid ho m\u00e1me skladom na Slovensku v \u0161tyroch baleniach: <strong>5 mg, 10 mg, 20 mg a 30 mg<\/strong>. Dod\u00e1va sa ako lyofilizovan\u00fd pr\u00e1\u0161ok v ampulke, objedn\u00e1vky odosielame do 24 hod\u00edn. Produkt je ur\u010den\u00fd v\u00fdhradne na laborat\u00f3rny a analytick\u00fd v\u00fdskum.<\/p>\n<p><em>Retatrutide sme predt\u00fdm pred\u00e1vali pod ozna\u010den\u00edm GLP-3 RTA \u2013 ide o ten ist\u00fd peptid.<\/em><\/p>\n<h2>\u010co je Retatrutide?<\/h2>\n<p>Retatrutide je peptid tzv. tretej gener\u00e1cie inkret\u00ednov\u00fdch anal\u00f3gov. K\u00fdm star\u0161ie molekuly aktivuj\u00fa jeden receptor (napr. semaglutid \u2013 GLP-1) alebo dva receptory (tirzepatid \u2013 GIP a GLP-1), Retatrutide sa v laborat\u00f3rnych podmienkach via\u017ee na <strong>tri receptory naraz<\/strong>. Preto sa mu hovor\u00ed aj \u201etriple agonista\u201c alebo neform\u00e1lne \u201eGLP-3\u201c.<\/p>\n<p>Molekulu vyvinula spolo\u010dnos\u0165 Eli Lilly a prv\u00fdkr\u00e1t ju podrobne pop\u00edsala \u0161t\u00fadia Coskun et al. v \u010dasopise <em>Cell Metabolism<\/em> (2022). Retatrutide v s\u00fa\u010dasnosti nie je registrovan\u00fd ako liek v E\u00da ani v USA a je predmetom prebiehaj\u00faceho klinick\u00e9ho v\u00fdskumu.<\/p>\n<h2>Ako Retatrutide p\u00f4sob\u00ed \u2013 tri receptory<\/h2>\n<h3>GLP-1 receptor (GLP-1R)<\/h3>\n<p>Receptor pre glukag\u00f3nu podobn\u00fd peptid 1. Vo v\u00fdskume sa sleduje jeho \u00faloha pri regul\u00e1cii sekr\u00e9cie inzul\u00ednu, vypr\u00e1zd\u0148ovania \u017eal\u00fadka a signaliz\u00e1cie s\u00fdtosti v centr\u00e1lnom nervovom syst\u00e9me.<\/p>\n<h3>GIP receptor (GIPR)<\/h3>\n<p>Receptor pre gluk\u00f3zovo-dependentn\u00fd inzulinotropn\u00fd polypeptid. Sk\u00fama sa jeho vplyv na sekr\u00e9ciu inzul\u00ednu z\u00e1visl\u00fa od gluk\u00f3zy a na metabolizmus tukov\u00e9ho tkaniva.<\/p>\n<h3>Glukag\u00f3nov\u00fd receptor (GcgR)<\/h3>\n<p>Aktiv\u00e1cia glukag\u00f3nov\u00e9ho receptora sa vo v\u00fdskume sp\u00e1ja so zv\u00fd\u0161en\u00fdm energetick\u00fdm v\u00fddajom, metabolizmom lipidov v pe\u010deni a termogen\u00e9zou. Pr\u00e1ve t\u00e1to tretia zlo\u017eka odli\u0161uje Retatrutide od du\u00e1lnych agonistov.<\/p>\n<h2>Retatrutide vs. Tirzepatide vs. Semaglutide<\/h2>\n<table>\n<thead>\n<tr>\n<th><\/th>\n<th>Semaglutide<\/th>\n<th>Tirzepatide<\/th>\n<th>Retatrutide<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Typ agonistu<\/td>\n<td>mono (1 receptor)<\/td>\n<td>du\u00e1lny (2 receptory)<\/td>\n<td>triple (3 receptory)<\/td>\n<\/tr>\n<tr>\n<td>Receptory<\/td>\n<td>GLP-1<\/td>\n<td>GIP + GLP-1<\/td>\n<td>GIP + GLP-1 + glukag\u00f3n<\/td>\n<\/tr>\n<tr>\n<td>Gener\u00e1cia<\/td>\n<td>1.<\/td>\n<td>2.<\/td>\n<td>3.<\/td>\n<\/tr>\n<tr>\n<td>Stav<\/td>\n<td>registrovan\u00fd liek<\/td>\n<td>registrovan\u00fd liek<\/td>\n<td>v klinickom v\u00fdskume<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Oblasti laborat\u00f3rneho v\u00fdskumu<\/h2>\n<ul>\n<li>energetick\u00e1 homeost\u00e1za a regul\u00e1cia energetick\u00e9ho v\u00fddaja<\/li>\n<li>metabolizmus gluk\u00f3zy a citlivos\u0165 na inzul\u00edn<\/li>\n<li>metabolizmus lipidov a pe\u010de\u0148ov\u00e9 modely (steat\u00f3za)<\/li>\n<li>receptorov\u00e1 farmakol\u00f3gia \u2013 porovnanie mono-, du\u00e1lnych a triple agonistov<\/li>\n<li>termogen\u00e9za a aktivita hned\u00e9ho tukov\u00e9ho tkaniva<\/li>\n<\/ul>\n<h2>Pre\u010do Retatrutide od DoktorPeptid<\/h2>\n<ul>\n<li><strong>4 ve\u013ekosti balenia<\/strong> \u2013 5 mg, 10 mg, 20 mg a 30 mg<\/li>\n<li><strong>Skladom na Slovensku<\/strong> \u2013 odoslanie do 24 hod\u00edn v pracovn\u00fdch d\u0148och<\/li>\n<li><strong>Doru\u010denie 1\u20132 dni<\/strong> na Slovensko aj do \u010ceskej republiky<\/li>\n<li><strong>Certifik\u00e1ty anal\u00fdzy (COA)<\/strong> ku ka\u017edej \u0161ar\u017ei<\/li>\n<li><strong>Platba kartou alebo na dobierku<\/strong><\/li>\n<li>hodnotenie obchodu <strong>4,9\/5<\/strong> od overen\u00fdch z\u00e1kazn\u00edkov<\/li>\n<\/ul>\n<h2>Technick\u00e9 parametre<\/h2>\n<table>\n<tbody>\n<tr>\n<td>N\u00e1zov<\/td>\n<td>Retatrutide (Retatrutid)<\/td>\n<\/tr>\n<tr>\n<td>In\u00e9 ozna\u010denia<\/td>\n<td>LY3437943, GLP-3 RTA, GLP-3 RT<\/td>\n<\/tr>\n<tr>\n<td>CAS<\/td>\n<td>2381089-83-2<\/td>\n<\/tr>\n<tr>\n<td>Molekulov\u00fd vzorec<\/td>\n<td>C<sub>221<\/sub>H<sub>342<\/sub>N<sub>46<\/sub>O<sub>68<\/sub><\/td>\n<\/tr>\n<tr>\n<td>Molekulov\u00e1 hmotnos\u0165<\/td>\n<td>cca 4731 g\/mol<\/td>\n<\/tr>\n<tr>\n<td>Forma<\/td>\n<td>lyofilizovan\u00fd pr\u00e1\u0161ok v ampulke<\/td>\n<\/tr>\n<tr>\n<td>Balenie<\/td>\n<td>5 mg \/ 10 mg \/ 20 mg \/ 30 mg<\/td>\n<\/tr>\n<tr>\n<td>Storage<\/td>\n<td>2\u20138 \u00b0C, chr\u00e1nen\u00e9 pred svetlom<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Rekon\u0161tit\u00facia a skladovanie<\/h2>\n<p>Retatrutide sa dod\u00e1va ako lyofilizovan\u00fd pr\u00e1\u0161ok, ktor\u00fd sa pred laborat\u00f3rnym pou\u017eit\u00edm rekon\u0161tituuje <a href=\"\/en\/product\/bakterio-staticka-voda\/\">bakteriostatickou vodou<\/a>. Neotvoren\u00fa ampulku skladujte v chlade pri teplote 2\u20138 \u00b0C. Chr\u00e1\u0148te pred mrazom, priamym svetlom a vysokou teplotou.<\/p>\n<h2>\u010co n\u00e1jdete v balen\u00ed<\/h2>\n<ul>\n<li>ampulka Retatrutide v zvolenej gram\u00e1\u017ei<\/li>\n<li>pevn\u00e9 balenie zabezpe\u010den\u00e9 proti po\u0161kodeniu pri preprave<\/li>\n<\/ul>\n<h2>Certifik\u00e1ty anal\u00fdzy<\/h2>\n<p>Certifik\u00e1ty anal\u00fdzy (COA) k jednotliv\u00fdm \u0161ar\u017eiam Retatrutide n\u00e1jdete v sekcii <a href=\"\/en\/coa\/\">Dokumenty COA<\/a>.<\/p>\n<h2>Doprava a platba<\/h2>\n<p>Retatrutide m\u00e1me na slovenskom sklade a objedn\u00e1vky odosielame do 24 hod\u00edn v pracovn\u00fdch d\u0148och. Doru\u010denie na Slovensko aj do \u010ceskej republiky trv\u00e1 spravidla 1\u20132 pracovn\u00e9 dni. Plati\u0165 m\u00f4\u017eete kartou online alebo na dobierku.<\/p>\n<h2>\u010casto kladen\u00e9 ot\u00e1zky o Retatrutide<\/h2>\n<h3>\u010co je Retatrutide?<\/h3>\n<p>Retatrutide (LY3437943) je syntetick\u00fd peptid, triple agonista receptorov GIP, GLP-1 a glukag\u00f3nu. Pou\u017e\u00edva sa vo v\u00fdskume metabolick\u00fdch procesov.<\/p>\n<h3>Retatrutid alebo Retatrutide \u2013 ak\u00fd je rozdiel?<\/h3>\n<p>\u017diadny. Retatrutide je medzin\u00e1rodn\u00fd (anglick\u00fd) n\u00e1zov, retatrutid je slovensk\u00fd a \u010desk\u00fd tvar toho ist\u00e9ho peptidu.<\/p>\n<h3>Je Retatrutide to ist\u00e9 ako GLP-3 RTA?<\/h3>\n<p>\u00c1no. GLP-3 RTA je ozna\u010denie, pod ktor\u00fdm sme Retatrutide pred\u00e1vali predt\u00fdm. Ide o rovnak\u00fd peptid.<\/p>\n<h3>Ak\u00e9 balenia Retatrutide pon\u00fakate?<\/h3>\n<p>Retatrutide m\u00e1me skladom v baleniach 5 mg, 10 mg, 20 mg a 30 mg.<\/p>\n<h3>Treba Retatrutide pred pou\u017eit\u00edm rekon\u0161tituova\u0165?<\/h3>\n<p>\u00c1no. Lyofilizovan\u00fd pr\u00e1\u0161ok sa v laborat\u00f3riu rekon\u0161tituuje bakteriostatickou vodou, ktor\u00fa m\u00f4\u017eete prida\u0165 do ko\u0161\u00edka priamo pri produkte.<\/p>\n<h3>Ako skladova\u0165 Retatrutide?<\/h3>\n<p>V chlade pri teplote 2\u20138 \u00b0C, chr\u00e1nen\u00fd pred svetlom a mrazom.<\/p>\n<h3>Ako dlho trv\u00e1 doru\u010denie?<\/h3>\n<p>Na Slovensko aj do \u010ceskej republiky spravidla 1\u20132 pracovn\u00e9 dni od odoslania.<\/p>\n<h3>\u010co ak je variant vypredan\u00fd?<\/h3>\n<p>Pri ka\u017edom variante vid\u00edte aktu\u00e1lnu dostupnos\u0165. Ak je vypredan\u00fd, m\u00f4\u017eete si nastavi\u0165 upozornenie na naskladnenie a ozveme sa v\u00e1m e-mailom, len \u010do tovar naskladn\u00edme.<\/p>\n<h3>Kde k\u00fapi\u0165 Retatrutide na Slovensku?<\/h3>\n<p>V na\u0161om e-shope, skladom v baleniach 5, 10, 20 a 30 mg (od 50,00 \u20ac), s odoslan\u00edm do 24 hod\u00edn v pracovn\u00fdch d\u0148och. Doru\u010dujeme na Slovensko aj do \u010ceskej republiky.<\/p>\n<h3>Je Retatrutide registrovan\u00fd liek?<\/h3>\n<p>Nie. Retatrutide nie je registrovan\u00fdm liekom a nie je ur\u010den\u00fd na hum\u00e1nne ani veterin\u00e1rne pou\u017eitie. Pred\u00e1vame ho v\u00fdhradne na vedeck\u00e9 a v\u00fdskumn\u00e9 \u00fa\u010dely.<\/p>\n<h2>Zdroje<\/h2>\n<ul>\n<li>Coskun T. et al. LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist for glycemic control and weight loss: From discovery to clinical proof of concept. <em>Cell Metabolism<\/em>, 2022.<\/li>\n<li>Jastreboff A. M. et al. Triple-Hormone-Receptor Agonist Retatrutide for Obesity \u2013 A Phase 2 Trial. <em>New England Journal of Medicine<\/em>, 2023.<\/li>\n<\/ul>\n<p><em>Uveden\u00e9 publik\u00e1cie s\u00fa nez\u00e1visl\u00fd v\u00fdskum tret\u00edch str\u00e1n a nie s\u00fa tvrden\u00edm o \u00fa\u010dinkoch pred\u00e1van\u00e9ho produktu.<\/em><\/p>\n<p><strong>Produkt nie je ur\u010den\u00fd na konzum\u00e1ciu. Iba na vedeck\u00e9 a v\u00fdskumn\u00e9 \u00fa\u010dely. Nie je registrovan\u00fdm liekom.<\/strong><\/p>\n<p><strong>S\u00favisiace \u010dl\u00e1nky:<\/strong> <a href=\"\/en\/kde-kupit-peptidy-na-slovensku\/\">Kde k\u00fapi\u0165 peptidy na Slovensku<\/a> \u00b7 <a href=\"\/en\/lacne-peptidy-cena\/\">Lacn\u00e9 peptidy: kedy n\u00edzka cena d\u00e1va zmysel<\/a>.<\/p>\n<p><!--dp-ilink--><\/p>\n<p>\u010eal\u0161ie produkty z rovnakej kateg\u00f3rie: <a href=\"https:\/\/doktorpeptid.sk\/en\/product-category\/metabolicke-peptidy\/\">Metabolic peptides<\/a>. Kompletn\u00fa ponuku n\u00e1jdete v sekcii <a href=\"https:\/\/doktorpeptid.sk\/en\/shop\/\">v\u0161etky produkty<\/a>.<\/p>","protected":false},"excerpt":{"rendered":"<p><strong>Retatrutide<\/strong> (retatrutid, GLP-3 RTA) skladom na Slovensku \u2013 triple agonista receptorov GIP, GLP-1 a glukag\u00f3nu. Lyofilizovan\u00fd pr\u00e1\u0161ok v ampulke, balenie 5, 10, 20 a 30 mg.<\/p>\n<p><strong>The product is not intended for consumption. For scientific and research purposes only.<\/strong><\/p>","protected":false},"featured_media":2092,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[31],"product_tag":[],"class_list":["post-423","product","type-product","status-publish","has-post-thumbnail","product_cat-metabolicke-peptidy","first","instock","taxable","shipping-taxable","purchasable","product-type-variable"],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/doktorpeptid.sk\/en\/wp-json\/wp\/v2\/product\/423","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/doktorpeptid.sk\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/doktorpeptid.sk\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/doktorpeptid.sk\/en\/wp-json\/wp\/v2\/comments?post=423"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/doktorpeptid.sk\/en\/wp-json\/wp\/v2\/media\/2092"}],"wp:attachment":[{"href":"https:\/\/doktorpeptid.sk\/en\/wp-json\/wp\/v2\/media?parent=423"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/doktorpeptid.sk\/en\/wp-json\/wp\/v2\/product_brand?post=423"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/doktorpeptid.sk\/en\/wp-json\/wp\/v2\/product_cat?post=423"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/doktorpeptid.sk\/en\/wp-json\/wp\/v2\/product_tag?post=423"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}