{"id":740,"date":"2026-05-25T23:09:11","date_gmt":"2026-05-25T21:09:11","guid":{"rendered":"https:\/\/doktorpeptid.sk\/?post_type=product&#038;p=740"},"modified":"2026-10-08T22:22:45","modified_gmt":"2026-10-08T20:22:45","slug":"tb-500","status":"publish","type":"product","link":"https:\/\/doktorpeptid.sk\/en\/product\/tb-500\/","title":{"rendered":"TB-500 \u2013 v\u00fdskumn\u00fd peptid 5 mg"},"content":{"rendered":"<h2>TB-500 \u2013 v\u00fdskumn\u00fd peptid skladom na Slovensku<\/h2>\n<p><strong>TB-500<\/strong> je syntetick\u00fd peptid odvoden\u00fd od <strong>tymoz\u00ednu beta-4<\/strong> (T\u03b24) \u2014 prirodzene sa vyskytuj\u00faceho prote\u00ednu, ktor\u00fd patr\u00ed medzi najhojnej\u0161ie zast\u00fapen\u00e9 v \u013eudsk\u00fdch bunk\u00e1ch a je pr\u00edtomn\u00fd takmer vo v\u0161etk\u00fdch tkaniv\u00e1ch a telesn\u00fdch tekutin\u00e1ch. Biologicky akt\u00edvnou \u010das\u0165ou molekuly je kr\u00e1tka <strong>akt\u00edn-via\u017euca dom\u00e9na<\/strong> so sekvenciou LKKTETQ, ktor\u00e1 je za v\u00e4\u010d\u0161inu sledovan\u00fdch vlastnost\u00ed zodpovedn\u00e1.<\/p>\n<p>Dod\u00e1vame ho <strong>lyofilizovan\u00fd<\/strong> v sklenenej ampulke so silik\u00f3novou z\u00e1tkou a hlin\u00edkov\u00fdm uz\u00e1verom, v balen\u00ed <strong>5 mg (40,00 \u20ac)<\/strong>.<\/p>\n<h2>Mechanizmus, ktor\u00fd sa v literat\u00fare sk\u00fama<\/h2>\n<p>\u00dastredn\u00fdm mechanizmom je v\u00e4zba na <strong>G-akt\u00edn<\/strong>. Tymoz\u00edn beta-4 p\u00f4sob\u00ed ako hlavn\u00fd sekvestra\u010dn\u00fd prote\u00edn akt\u00ednov\u00e9ho monom\u00e9ru \u2014 reguluje rovnov\u00e1hu medzi vo\u013en\u00fdm akt\u00ednom a jeho polymerizovanou formou, a t\u00fdm ovplyv\u0148uje prestavbu cytoskeletu, migr\u00e1ciu buniek a ich schopnos\u0165 presun\u00fa\u0165 sa na miesto po\u0161kodenia.<\/p>\n<p>V publikovan\u00fdch modeloch sa \u010falej sleduje vplyv na angiogen\u00e9zu, na diferenci\u00e1ciu endotelov\u00fdch buniek a na regul\u00e1ciu z\u00e1palov\u00fdch cytok\u00ednov. Uveden\u00e9 je predmetom prebiehaj\u00faceho v\u00fdskumu a nepredstavuje tvrdenie o \u00fa\u010dinku u \u013eud\u00ed.<\/p>\n<h2>\u0160pecifik\u00e1cia produktu<\/h2>\n<table>\n<tr>\n<th>N\u00e1zov<\/th>\n<td>TB-500 (fragment tymoz\u00ednu beta-4)<\/td>\n<\/tr>\n<tr>\n<th>CAS<\/th>\n<td>885340-08-9<\/td>\n<\/tr>\n<tr>\n<th>Akt\u00edvna dom\u00e9na<\/th>\n<td>LKKTETQ (akt\u00edn-via\u017euca sekvencia)<\/td>\n<\/tr>\n<tr>\n<th>P\u00f4vodn\u00fd prote\u00edn<\/th>\n<td>tymoz\u00edn beta-4, 43 aminokysel\u00edn<\/td>\n<\/tr>\n<tr>\n<th>Balenie<\/th>\n<td>5 mg v ampulke<\/td>\n<\/tr>\n<tr>\n<th><\/th>\n<td>\u2265 99 %<\/td>\n<\/tr>\n<tr>\n<th>Forma<\/th>\n<td>lyofilizovan\u00fd biely pr\u00e1\u0161ok<\/td>\n<\/tr>\n<tr>\n<th>Ur\u010denie<\/th>\n<td>v\u00fdhradne laborat\u00f3rny a analytick\u00fd v\u00fdskum<\/td>\n<\/tr>\n<\/table>\n<h2>Rekon\u0161tit\u00facia a manipul\u00e1cia v laborat\u00f3riu<\/h2>\n<p>Lyofiliz\u00e1t sa \u0161tandardne rozp\u00fa\u0161\u0165a <a href=\"\/en\/product\/bakterio-staticka-voda\/\">bakteriostatickou vodou<\/a> (0,9 % benzylalkohol), pr\u00edpadne sterilnou vodou na injekciu, ak sa roztok spotrebuje naraz. Rozp\u00fa\u0161\u0165adlo prid\u00e1vajte pomaly po vn\u00fatornej stene ampulky, nie priamo na pr\u00e1\u0161ok. Ampulkou <strong>netrepte<\/strong> \u2014 peptidov\u00fd re\u0165azec je citliv\u00fd na mechanick\u00e9 nam\u00e1hanie a penenie. Nechajte ju st\u00e1\u0165 pri izbovej teplote, k\u00fdm sa obsah samovo\u013ene nerozpust\u00ed, a potom ju jemne ot\u00e1\u010dajte medzi prstami. Z\u00e1tku pred ka\u017ed\u00fdm odberom dezinfikujte izopropylalkoholom a nechajte oschn\u00fa\u0165.<\/p>\n<h2>Skladovanie a stabilita<\/h2>\n<ul>\n<li><strong>Nerozpusten\u00fd lyofiliz\u00e1t:<\/strong> \u221220 \u00b0C, chr\u00e1nen\u00fd pred svetlom a vlhkos\u0165ou. V tomto stave je peptid stabiln\u00fd dlhodobo.<\/li>\n<li><strong>Kr\u00e1tkodobo pri transporte:<\/strong> izbov\u00e1 teplota po dobu nieko\u013ek\u00fdch dn\u00ed.<\/li>\n<li><strong>Po rekon\u0161tit\u00facii:<\/strong> 2 \u2013 8 \u00b0C v chladni\u010dke, chr\u00e1nen\u00e9 pred svetlom. Roztok nezmrazujte a nevystavujte opakovan\u00fdm cyklom zmrazenia a rozmrazenia.<\/li>\n<\/ul>\n<h2>Balenie a doru\u010denie<\/h2>\n<p>Produkt posielame v pevnom balen\u00ed zabezpe\u010denom proti po\u0161kodeniu po\u010das prepravy.<\/p>\n<p>Certifik\u00e1ty anal\u00fdzy (COA) k jednotliv\u00fdm \u0161ar\u017eiam n\u00e1jdete v sekcii <a href=\"\/en\/coa\/\">Dokumenty COA<\/a>.<\/p>\n<h2>Doprava, platba a vr\u00e1tenie<\/h2>\n<p>Objedn\u00e1vky prijat\u00e9 v pracovn\u00fd de\u0148 odosielame <strong>do 24 hod\u00edn<\/strong>. Doprava na Slovensku od 3,30 \u20ac, pri objedn\u00e1vke nad 150 \u20ac zadarmo. Platba kartou alebo prevodom. Tovar m\u00f4\u017eete vr\u00e1ti\u0165 do 14 dn\u00ed od doru\u010denia.<\/p>\n<h2>Frequently asked questions<\/h2>\n<h3>\u010co je TB-500?<\/h3>\n<p>TB-500 je syntetick\u00fd peptid odvoden\u00fd od tymoz\u00ednu beta-4, prirodzen\u00e9ho prote\u00ednu pr\u00edtomn\u00e9ho vo v\u00e4\u010d\u0161ine \u013eudsk\u00fdch tkan\u00edv. V na\u0161ej ponuke je ako lyofilizovan\u00fd peptid ur\u010den\u00fd v\u00fdhradne na laborat\u00f3rny v\u00fdskum.<\/p>\n<h3>Ak\u00fd je rozdiel medzi TB-500 a tymoz\u00ednom beta-4?<\/h3>\n<p>Tymoz\u00edn beta-4 je cel\u00fd 43-aminokyselinov\u00fd prote\u00edn. TB-500 je jeho syntetick\u00e1, krat\u0161ia forma obsahuj\u00faca akt\u00edvnu akt\u00edn-via\u017eucu dom\u00e9nu LKKTETQ.<\/p>\n<h3>Ako TB-500 funguje v sk\u00faman\u00fdch modeloch?<\/h3>\n<p>Via\u017ee sa na G-akt\u00edn a ovplyv\u0148uje rovnov\u00e1hu akt\u00ednov\u00e9ho cytoskeletu. V publikovan\u00fdch pr\u00e1cach sa sleduje aj vplyv na angiogen\u00e9zu a migr\u00e1ciu buniek.<\/p>\n<h3>Ko\u013eko stoj\u00ed TB-500?<\/h3>\n<p>5 mg balenie stoj\u00ed 40,00 \u20ac a je skladom na Slovensku.<\/p>\n<h3>\u010c\u00edm sa TB-500 rekon\u0161tituuje?<\/h3>\n<p>Naj\u010dastej\u0161ie bakteriostatickou vodou s 0,9 % benzylalkoholu. Rozp\u00fa\u0161\u0165adlo sa prid\u00e1va po stene ampulky, obsahom sa netrepe.<\/p>\n<h3>Ako sa TB-500 skladuje?<\/h3>\n<p>Lyofiliz\u00e1t pri \u221220 \u00b0C chr\u00e1nen\u00fd pred svetlom. Po rekon\u0161tit\u00facii v chladni\u010dke pri 2 \u2013 8 \u00b0C, bez opakovan\u00e9ho zmrazovania.<\/p>\n<h3>Je TB-500 ur\u010den\u00fd na hum\u00e1nne pou\u017eitie?<\/h3>\n<p>Nie. Produkt je ur\u010den\u00fd v\u00fdhradne na vedeck\u00e9 a laborat\u00f3rne \u00fa\u010dely. Nie je liekom ani v\u00fd\u017eivov\u00fdm doplnkom a nie je ur\u010den\u00fd na konzum\u00e1ciu.<\/p>\n<p><strong>Warning:<\/strong> TB-500 pred\u00e1vame v\u00fdhradne na v\u00fdskumn\u00e9 a analytick\u00e9 \u00fa\u010dely. Nie je liekom, v\u00fd\u017eivov\u00fdm doplnkom ani potravinou a nie je ur\u010den\u00fd na konzum\u00e1ciu ani na podanie \u013eu\u010fom \u010di zvierat\u00e1m. Kupuj\u00faci zodpoved\u00e1 za nakladanie s l\u00e1tkou v s\u00falade s platnou legislat\u00edvou a intern\u00fdmi predpismi svojho pracoviska.<\/p>","protected":false},"excerpt":{"rendered":"<p>TB-500 skladom na Slovensku. odoslanie do 24 hod\u00edn, doprava SK a \u010cR.<\/p>\n<p><strong>The product is not intended for consumption. For scientific and research purposes only.<\/strong><\/p>","protected":false},"featured_media":1890,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[29],"product_tag":[],"class_list":["post-740","product","type-product","status-publish","has-post-thumbnail","product_cat-regeneracne-peptidy","first","instock","taxable","shipping-taxable","purchasable","product-type-simple"],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/doktorpeptid.sk\/en\/wp-json\/wp\/v2\/product\/740","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/doktorpeptid.sk\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/doktorpeptid.sk\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/doktorpeptid.sk\/en\/wp-json\/wp\/v2\/comments?post=740"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/doktorpeptid.sk\/en\/wp-json\/wp\/v2\/media\/1890"}],"wp:attachment":[{"href":"https:\/\/doktorpeptid.sk\/en\/wp-json\/wp\/v2\/media?parent=740"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/doktorpeptid.sk\/en\/wp-json\/wp\/v2\/product_brand?post=740"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/doktorpeptid.sk\/en\/wp-json\/wp\/v2\/product_cat?post=740"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/doktorpeptid.sk\/en\/wp-json\/wp\/v2\/product_tag?post=740"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}